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Related Experiment Video

Updated: May 13, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Memory reconsolidation: time to change your mind.

Matthew R Bailey¹, Peter D Balsam

¹Department of Psychology, Columbia University, New York, NY 10027, USA. mrb2225@columbia.edu

Current Biology : CB

|March 23, 2013

Summary

Temporal expectations are crucial for fear memories. Modifying these expectations can update and reconsolidate existing fear memories, offering new insights into fear learning.

Area of Science:

Neuroscience
Cognitive Psychology
Memory Research

Background:

Fear memories are essential for survival, but maladaptive fear can lead to debilitating conditions like PTSD.
Understanding the mechanisms of fear memory consolidation and updating is critical for developing effective treatments.

Purpose of the Study:

To investigate the role of temporal expectations in the formation and modification of fear memories.
To determine if altering temporal threat expectations can trigger fear memory updating and reconsolidation.

Main Methods:

Utilizing fear conditioning paradigms in a controlled laboratory setting.
Employing psychophysiological measures (e.g., skin conductance) and subjective ratings to assess fear responses.
Manipulating temporal cues associated with threat to alter expectations.

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Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Published on: August 24, 2012

Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker

Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker

Published on: December 18, 2014

Related Experiment Videos

Last Updated: May 13, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Published on: August 24, 2012

Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker

Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker

Published on: December 18, 2014

Main Results:

Temporal expectations were identified as a significant component of established fear memories.
Changes in temporal threat expectations were sufficient to induce the updating and subsequent reconsolidation of previously learned fear associations.

Conclusions:

Temporal expectation is a fundamental element in the architecture of fear memory.
Targeting and modifying temporal threat expectations presents a potential therapeutic strategy for fear-related disorders.