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Assessment of the relationship between aortic pulse wave velocity and aortic arch calcification

Serkan Oztürk1, Davut Baltacı, Suzi Selim Ayhan

  • 1Department of Cardiology, Abant İzzet Baysal University, Bolu, Turkey. drserkan69@hotmail.com

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|March 23, 2013
PubMed

Insights

Aortic calcification is linked to increased aortic pulse wave velocity (PWV), a key indicator of arterial stiffness. This study highlights the association between calcification and cardiovascular health markers.

Area of Science:

  • Cardiovascular Medicine
  • Radiology
  • Vascular Biology

Background:

  • Aortic calcification is a marker of atherosclerosis.
  • Arterial stiffness is an independent predictor of cardiovascular events.
  • The relationship between aortic calcification and arterial stiffness requires further investigation.

Purpose of the Study:

  • To assess arterial stiffness parameters in patients with and without aortic arch calcification.
  • To investigate the relationship between aortic calcification and arterial stiffness.

Main Methods:

  • Chest X-ray was used to identify aortic arch calcification.
  • Arterial stiffness parameters including aortic pulse wave velocity (PWV), augmentation pressure (AP), augmentation index (AIx), and AIx@75 were measured non-invasively.
  • Patients with symptomatic vascular disease were excluded.

Main Results:

  • Patients with aortic arch calcification (Group I) showed significantly higher AP (p=0.002) and aortic PWV (p<0.0001) compared to controls (Group II).
  • AIx and AIx@75 were similar between the groups.
  • No significant differences in demographic characteristics, medications, or serum lipids were observed.

Conclusions:

  • Aortic calcification, identified by chest radiography, is associated with increased aortic PWV.
  • This suggests that aortic calcification may contribute to heightened arterial stiffness.
Abstract

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