Related Experiment Video
Updated: May 13, 2026
A Standardized Protocol for Functional Motor Mapping Using Navigated Transcranial Magnetic Stimulation
Published on: February 27, 2026
[Neurophysiological assisted transsulcal approach to a high grade glioma without affect neither motor nor
Jesús Pastor1, Paloma Pulido-Rivas, Rafael G Sola
1Servicio de Neurofisiología Clínica, Unidadde Cirugía de la Epilepsia, Hospital Universitario de la Princesa, Clínica Nuestra Señora del Rosario, 28006 Madrid, Spain. jpastor.hlpr@salud.madrid.org
Introduction:
Intraoperative mapping and neuronavigation permitted a safe approach through the rolandic sulcus, minimizing the impact onto the motor or somatosensory functions. Fluorescence-guide resection defines a limit that allows a total resection without exceed the border of the tumor.
Case Report:
A 39-year-old man who was operated by a tumor placed into the rolandic area. With the patient anesthetized (propofol+remyfentanil), we performed cortical mapping, neuronavigation and fluorescence-guide resection with 5-aminolevulinic acid. Post-resection neurophysiologic assessment showed a minor and highly localized effect onto the somato-sensory system.
Conclusion:
Rolandic area surgery can be safely performed in anesthetized patients when extensive neurophysiological, anatomical and biological assessments are performed.
