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Updated: May 13, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
Previous cyclodestruction is a risk factor for late-onset hypotony and suprachoroidal haemorrhage after glaucoma
André Rosentreter1, Stergiani Gaki, Alexandra Lappas
1Center of Ophthalmology, University of Cologne, Joseph-Stelzmann-Strasse 9, Cologne, Germany. andre.rosentreter@googlemail.com
Insights
Previous cyclodestructive procedures increase risks for glaucoma drainage device (GDD) surgery patients, leading to higher rates of suprachoroidal hemorrhage and late-onset hypotony. Further research is needed to confirm these findings.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Surgical Outcomes
Background:
- Glaucoma drainage device (GDD) surgery is a common treatment for refractory glaucoma.
- Previous cyclodestructive procedures are sometimes performed to lower intraocular pressure (IOP) before GDD implantation.
- The impact of prior cyclodestructive interventions on GDD surgery outcomes is not fully understood.
Purpose of the Study:
- To evaluate the influence of previous cyclodestructive procedures on the outcomes of glaucoma drainage device (GDD) surgery.
- To compare intraocular pressure (IOP), medication requirements, and complication rates between patients with and without prior cyclodestructive surgery.
Main Methods:
- Retrospective analysis of 110 patients undergoing GDD surgery (Baerveldt implants).
- Patients were divided into two groups: those with prior cyclodestructive surgery (n=47) and those without (n=63).
- Data collected included preoperative and postoperative IOP, medication score, visual acuity, and surgical complications.
Main Results:
- Patients with prior cyclodestructive surgery had a higher incidence of suprachoroidal hemorrhage (12.8% vs 0%, p=0.01).
- Late-onset hypotony (>6 weeks post-op) was significantly more frequent in the prior cyclodestructive surgery group (19.1% vs 4.8%, p=0.03).
- No significant difference in mean preoperative IOP or medication score was observed between groups.
Conclusions:
- Previous cyclodestructive procedures appear to be a significant risk factor for suprachoroidal hemorrhage following GDD surgery.
- A history of cyclodestructive interventions may also increase the risk of late-onset hypotony after GDD implantation.
- These findings suggest careful consideration of prior surgical history when planning GDD surgery.
Aim:
To investigate whether previous cyclodestructive (eg, cyclophotocoagulation and cyclocryodestruction) procedures have any influence on the general outcome and pressure level after glaucoma drainage device (GDD) surgery.
Methods:
Retrospective analysis of 110 consecutive patients who had undergone GDD (Baerveldt 250 mm(2) and 350 mm(2) implant, AMO, USA) surgery with a minimum follow-up of 3 months. The patients were divided into patients with previous cyclodestructive surgery before GDD surgery (I; 47 patients) and patients without previous cyclodestructive surgery (II; 63 patients). Intraocular pressure (IOP), medication score, best-corrected visual acuity and surgical treatments were recorded before and after drainage device implantation.
Results:
Patients of group I had a mean preoperative IOP of 32.1 mm Hg and a mean medication score of 4.8; patients of group II had a mean preoperative IOP of 29.2 mm Hg (p=0.18) and a mean medication score of 4.9 (p=0.84). All patients who developed suprachoroidal haemorrhage (six cases) belonged to group I (6/47=12.8%), no patient of group II (0/63=0%) developed suprachoroidal haemorrhage (Fisher's test: p=0.01). Twelve patients developed late-onset (>6 weeks after GDD surgery) hypotony, nine of them belonging to group I (9/47=19.1%) and three of them to group II (3/63=4.8%) (Fisher's test: p=0.03).
Conclusions:
While taking potential bias arising from the retrospective nature of the study into consideration, a history of previous cyclodestructive procedures before GDD surgery seems to be a major risk factor for suprachoroidal haemorrhage and for late-onset postoperative hypotony.
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