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Comparison of topical tramadol and ketamine in pain treatment after tonsillectomy

Umit Y Tekelioglu1, Tayfun Apuhan, Akcan Akkaya

  • 1Department of Anesthesiology and Reanimation, Abant Izzet Baysal University Medical School, Bolu, Turkey. drtekelioglu@yahoo.com

Paediatric Anaesthesia
|March 26, 2013
PubMed

Insights

Topical ketamine and tramadol effectively reduced pain after tonsillectomy in children. Both agents were safe and easy to administer, offering a promising approach to managing post-tonsillectomy pain.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Pain Management

Background:

  • Tonsillectomy often results in significant postoperative pain, necessitating substantial opioid analgesia.
  • Effective pain management post-tonsillectomy remains a clinical challenge despite various surgical and anesthetic techniques.

Purpose of the Study:

  • To evaluate topical ketamine and tramadol for early postoperative pain in pediatric tonsillectomy.
  • To assess associated symptoms like nausea, vomiting, swallowing difficulty, and sore throat.

Main Methods:

  • 60 children (4-10 years) undergoing tonsillectomy were randomized into three groups.
  • Groups received topical ketamine, tramadol, or saline (control) in tonsillar fossae.
  • Pain scores, sedation, nausea, vomiting, and sore throat were evaluated using standardized scales.

Main Results:

  • Both topical ketamine and tramadol significantly reduced pain scores compared to the control group.
  • No significant differences were observed in pain or sore throat between ketamine and tramadol groups.
  • Both agents were found to be safe, with no significant adverse effects on vital signs.

Conclusions:

  • Topical ketamine and tramadol represent safe and effective analgesic options for pediatric tonsillectomy.
  • These agents offer an easy-to-administer approach to mitigate post-tonsillectomy pain.
  • Further research could explore long-term efficacy and optimal dosing.
Abstract

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