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Published on: April 5, 2011
Syncope and polymorphic ventricular tachycardia in the setting of a febrile illness
Marta Noris1, Andrés Carrillo, Oscar Campuzano
1Hospital Universitario Son Espases. Unidad Coronaria. Palma de Mallorca, España.
Abstract:
An asymptomatic woman with no clinical history consulted for pneumonia-induced fever; she then presented episodes of syncope due to polymorphic ventricular tachycardia and ECG alterations compatible with Brugada syndrome. Genetic studies showed no alterations in the SCN5A gene but other polymorphisms were observed. Further genetic studies are required to elucidate the pathophysiological mechanisms of fever and the function of sodium channels.
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