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Related Concept Videos

Brainstem01:19

Brainstem

The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...

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Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
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Published on: September 25, 2012

Brainstem gliomas.

Ana Ramos1, Amaya Hilario, Alfonso Lagares

  • 1Neuroradiology, Department of Radiology, Hospital 12 de Octubre, Madrid, Spain. ramosana3@yahoo.es

Seminars in Ultrasound, CT, and MR
|March 26, 2013
PubMed
Summary

Brainstem gliomas are now understood as a diverse group of tumors, not a single entity. Advanced magnetic resonance (MR) imaging techniques aid in diagnosing these heterogeneous pediatric and adult brainstem gliomas.

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Area of Science:

  • Neuro-oncology
  • Radiology
  • Pediatric Oncology

Background:

  • Brainstem gliomas were historically viewed as a uniform tumor type.
  • Magnetic resonance (MR) imaging advancements have revealed their heterogeneity.
  • Tumor subtypes differ in onset, presentation, behavior, and natural history.

Purpose of the Study:

  • To describe the various subtypes of pediatric and adult brainstem gliomas.
  • To highlight the role of advanced MR imaging in diagnosis.

Main Methods:

  • Review of current literature on brainstem gliomas.
  • Focus on advanced MR techniques: MR spectroscopy, MR perfusion, and diffusion tensor imaging.

Main Results:

  • Brainstem gliomas represent a heterogeneous group of neoplasms.
  • Advanced MR imaging techniques can suggest histopathologic diagnosis.
  • Subtypes exhibit distinct clinical and radiologic features.

Conclusions:

  • Brainstem gliomas are a heterogeneous group requiring subtype-specific understanding.
  • Advanced MR imaging is crucial for non-invasive diagnosis and characterization.
  • Further research into specific subtypes will improve patient outcomes.