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Published on: November 16, 2016
[Epidemiology and clinical features of Streptococcus pyogenes bacteremia in Cartagena (Murcia, Spain)]
Amaya Jimeno-Almazán1, Montserrat Viqueira-Gonzalez, María Del Mar Alcalde
1Servicio de Medicina Interna, Sección de Enfermedades Infecciosas, Hospital Universitario Santa Lucía, Cartagena, Murcia, España. doc.jimeno@hotmail.com
Introduction:
A gradual increase in severe cases due to Streptococcus pyogenes or Streptococcus beta-hemolytic group A (SGA), has been detected in the last few decades.
Methods:
Retrospective study of bacteremia due to S.pyogenes detected between January 2009 and January 2013 in Cartagena. The annual incidence for severe bacteremia has been estimated.
Results:
Thirteen cases of SGA bacteremia were recorded. The incidence increased from 0.37 in 2009 to 2.5 cases/100,000 inhabitants in 2012. The predominant focus was skin and soft tissue infections (53%). Early mortality was 20%.
Conclusion:
Severe streptococcal disease is rare, but affects individuals with good functional status, and is associated with a high mortality.
Insights
Severe Streptococcus pyogenes infections, also known as Group A Streptococcus (SGA) bacteremia, are increasing. This rare but serious condition has a high mortality rate, particularly from skin and soft tissue infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Context:
- A rise in severe Streptococcus pyogenes infections has been observed globally.
- Streptococcus beta-hemolytic group A (SGA) is a significant pathogen.
- Understanding local incidence and outcomes is crucial for public health.
Purpose:
- To determine the incidence of severe Streptococcus pyogenes bacteremia in Cartagena.
- To analyze the clinical characteristics and outcomes of SGA bacteremia.
- To identify risk factors and trends in severe streptococcal disease.
Summary:
- A retrospective study identified 13 cases of SGA bacteremia between 2009 and 2013 in Cartagena.
- The incidence of severe bacteremia rose from 0.37 to 2.5 cases per 100,000 inhabitants.
- Skin and soft tissue infections were the primary source (53%), with a 20% early mortality rate.
Impact:
- Severe streptococcal disease, though rare, impacts healthy individuals.
- The study highlights the potential for high mortality associated with SGA bacteremia.
- Findings underscore the need for vigilance and prompt treatment of invasive S. pyogenes infections.
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