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Intracranial epidermoid cysts.

S L Howng1, A L Kwan, S L Hwang

  • 1Department of Neurosurgery, Kaohsiung Medical College, Taiwan, Republic of China.

Gaoxiong Yi Xue Ke Xue Za Zhi = the Kaohsiung Journal of Medical Sciences
|February 1, 1990
PubMed
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Intracranial epidermoid cysts are rare brain tumors. Complete surgical removal is recommended for optimal outcomes, particularly in cases of severe trigeminal neuralgia.

Area of Science:

  • Neurosurgery
  • Neuropathology
  • Neuroradiology

Background:

  • Intracranial epidermoid cysts are uncommon neoplasms, representing 0-8% of all brain tumors.
  • This study reviewed ten cases of intracranial epidermoid cysts diagnosed over a 3-year period, accounting for 4% of all brain tumors at the institution.

Purpose of the Study:

  • To analyze the clinical presentation, diagnostic imaging features, and surgical outcomes of intracranial epidermoid cysts.
  • To emphasize the importance of gross total resection for benign intracranial epidermoid cysts.

Main Methods:

  • Retrospective review of ten patients with pathologically verified intracranial epidermoid cysts.
  • Diagnostic evaluation primarily utilized high-resolution computerized tomography (CT).
  • Surgical outcomes were assessed based on the extent of resection and patient recovery.

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Main Results:

  • The study included ten patients (6 women, 4 men) aged 18-58 years with a mean neurological deficit history of 4.3 years.
  • Lesion locations varied, including intracerebral, hourglass-shaped, suprasellar, and cerebellopontine (C-P) angle.
  • High-resolution CT revealed hypodense, non-enhanced masses; calcification was noted in three patients.

Conclusions:

  • Intracranial epidermoid cysts present with diverse clinical symptoms based on location.
  • Gross total resection is the preferred surgical approach when feasible, offering excellent post-operative results.
  • Surgical intervention is particularly beneficial for patients suffering from debilitating trigeminal neuralgia.