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Published on: December 5, 2025
Reconstruction of extensive lip and perioral defects after tumor excision
Guowen Sun1, Mingxing Lu, Qingang Hu
1Department of Oral and Maxillofacial Surgery, School of Stomatology, Nanjing University Medical Center, Nanjing University, Stomatological Hospital of Nanjing, Nanjing, PR China.
Objective:
The purpose of this study was to assess the clinical features, treatments, and results of extensive lip and perioral defects after tumor excision.
Methods:
This is a retrospective study of patients with extensive lip and perioral defects who underwent surgical interventions during the 7-year period from April 2005 to April 2012. The reconstructive procedures of lip and perioral defects were mainly performed with regional flaps or free flaps.
Results:
Eleven patients with extensive lip and perioral defects were identified, and immediate lip and perioral defects reconstruction was performed with the folded free radial forearm flap in 2 patients, the free radial forearm flap and the forehead island flap in 1 patient, the pectoralis major myocutaneous flap in 2 patients, the submental island flap and the nasolabial flap in 1 patient, the folded thinned anterolateral thigh flap in 4 patients, and double skin paddle anterolateral thigh flaps and adjacent flap in 1 patient. All patients had good oral competence, and the cosmetic results were acceptable.
Conclusions:
Reconstruction of extensive lip and perioral defects after tumor excision is a challenge for the plastic surgeon. It should take into account the patient's condition, local tissue characteristics, previous treatments, functional needs, cosmetic aspects, and so on. The surgeon might need to reconstruct the lip with regional flaps or free flaps.