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Updated: May 13, 2026

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Anterior skull base oncocytoma.
Fernando López1, Blanca Vivanco, Carlos Suárez
1Department of Otorhinolaringology, Unit of Skull Base, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain. flopez_1981@yahoo.es
The Journal of Craniofacial Surgery
|March 26, 2013
Summary
This study reports a rare anterior skull base oncocytoma in a 44-year-old male. The patient achieved complete tumor resection and remains disease-free, highlighting a novel surgical approach.
Area of Science:
- Oncology
- Neurosurgery
- Pathology
Background:
- Oncocytic neoplasms, characterized by oncocytes rich in mitochondria, are typically benign salivary gland tumors.
- While rare in the sinonasal tract, oncocytomas seldom involve the anterior skull base.
Observation:
- A 44-year-old male presented with an oncocytoma involving the anterior skull base.
- Preoperative carotid angiography and embolization were performed.
- The tumor was completely resected via an expanded endoscopic endonasal anterior craniofacial resection with low morbidity.
Findings:
- Pathological diagnosis confirmed oncocytoma.
- The patient has remained disease-free for 36 months post-treatment.
- This case may represent the first reported instance of an anterior skull base oncocytoma.
Implications:
- This case expands the known anatomical locations for oncocytomas.
- Endoscopic endonasal resection offers a minimally invasive approach for anterior skull base tumors.
- Further research into sinonasal and skull base oncocytomas is warranted.
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