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Updated: May 13, 2026

Hybrid Printing for the Fabrication of Smart Sensors

Hybrid Printing for the Fabrication of Smart Sensors

Published on: January 31, 2019

Microfluidic impact printer with interchangeable cartridges for versatile non-contact multiplexed micropatterning.

Yuzhe Ding¹, Eric Huang, Kit S Lam

¹Micro-Nano Innovations (MiNI) Laboratory, Biomedical Engineering, University of California, Davis, CA, USA.

|March 26, 2013

Summary

A novel Microfluidic Impact Printer (MI-Printer) combines inkjet and impact printing for versatile biopatterning. This platform offers high resolution and multiplexed capabilities for advanced biomedical research.

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Area of Science:

Biomedical Engineering
Materials Science
Microfluidics

Background:

Biopatterning is crucial for cellular microenvironments but faces challenges in biocompatibility and reagent availability.
Existing methods often struggle with cross-contamination and limited adaptability for complex media.

Purpose of the Study:

To develop a versatile multiplexed micropatterning platform, the Microfluidic Impact Printer (MI-Printer).
To overcome limitations of current biopatterning techniques by combining inkjet and impact printing features.

Main Methods:

Development of the Microfluidic Impact Printer (MI-Printer) platform.
Experimental characterization and theoretical analysis of printing resolution.
Demonstration of multiplexed and combinatorial printing functionalities.

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The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter

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Published on: April 22, 2014

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Last Updated: May 13, 2026

Hybrid Printing for the Fabrication of Smart Sensors

Hybrid Printing for the Fabrication of Smart Sensors

Published on: January 31, 2019

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter

The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter

Published on: April 22, 2014

Main Results:

Achieved optimal printing resolution of 80 μm with minimal dead volume and no cross-contamination.
Demonstrated multiplexed and combinatorial printing with less than 10 μm misalignment.
Successfully implemented molecular and biological patterning for biomedical applications.

Conclusions:

The MI-Printer platform offers a versatile, high-throughput solution for biopatterning.
Its features, including biocompatibility and adaptability, are highly desirable for laboratory R&D.
The MI-Printer shows significant utility for emerging biomedical applications.