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Updated: May 13, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Current and evolving clinical applications of multidetector cardiac CT in assessment of structural heart disease
Arthur Nasis1, Philip M Mottram, James D Cameron
1Monash Cardiovascular Research Centre, MonashHeart, Southern Health, Monash University Department of Medicine, 246 Clayton Rd, Clayton 3168, Victoria, Australia.
Insights
Multidetector computed tomography (CT) offers valuable noncoronary cardiac assessments beyond coronary artery disease evaluation. This imaging technique is crucial for pre-procedural planning and complements other modalities for comprehensive cardiac imaging.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Cardiac CT
Background:
- Multidetector computed tomography (CT) is established for coronary artery disease evaluation.
- Beyond coronary assessment, MDCT provides detailed noncoronary cardiac and pulmonary venous anatomy.
- MDCT is increasingly recognized for periprocedural evaluation in structural heart interventions.
Purpose of the Study:
- To review noncoronary cardiac structures evaluated by multidetector CT.
- To outline established and evolving clinical applications of MDCT in cardiac imaging.
- To highlight MDCT's role in assessing structural heart disease and periprocedural planning.
Main Methods:
- Review of existing literature and clinical applications of multidetector CT.
- Focus on noncoronary cardiac structures and their anatomical assessment.
- Analysis of MDCT's utility in electrophysiology and percutaneous structural interventions.
Main Results:
- MDCT provides essential anatomical information for electrophysiology procedures.
- MDCT plays a key role in periprocedural evaluation for transcatheter aortic valve replacement and left atrial appendage occlusion.
- MDCT is increasingly used alongside echocardiography and MRI for comprehensive cardiac assessment.
Conclusions:
- Multidetector CT is a versatile tool for evaluating noncoronary cardiac structures.
- MDCT has established and emerging roles in diagnosing structural heart disease and guiding interventions.
- MDCT serves as a complementary imaging modality for detailed cardiac evaluation.
Abstract:
Multidetector computed tomography (CT) has an established role in the evaluation of selected patients suspected of having coronary disease; however, in addition to coronary assessment, multidetector CT can be used to evaluate numerous noncoronary structures in the same examination. In particular, the use of multidetector CT to provide pulmonary and cardiac venous anatomic information prior to electrophysiology procedures is well established, and its important role in the periprocedural evaluation of patients undergoing percutaneous procedures, such as transcatheter aortic valve replacement and left atrial appendage device occlusion, is being increasingly recognized. Such advances have resulted in multidetector CT being increasingly used as a complementary imaging technique to echocardiography and magnetic resonance imaging for the comprehensive evaluation of cardiac structure and function in particular clinical situations. This review provides an overview of the noncoronary cardiac structures that can be evaluated with multidetector CT, and outlines the established appropriate clinical uses of multidetector CT in the assessment of structural heart disease, as well as evolving periprocedural clinical applications.
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