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Updated: May 13, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
[Beating heart coronary artery bypass: 100 cases]
Atef Ben Youssef1, Mouna Bousnina, Sonia Ouerghi
1Universite Tunis, El Manar, Tunisie.
Off-pump coronary artery bypass grafting, also known as beating heart surgery, offers favorable outcomes for patients, including those with multi-vessel disease and high-risk profiles.
Area of Science:
- Cardiovascular Surgery
- Cardiac Anesthesia
Context:
- Coronary artery bypass grafting (CABG) traditionally involves cardiopulmonary bypass, which is associated with potential risks.
- Off-pump CABG (OPCAB) has emerged as an alternative surgical strategy.
- This study evaluates the outcomes of OPCAB in a cohort of patients.
Purpose:
- To assess the clinical outcomes and safety of off-pump coronary artery bypass grafting.
- To determine the efficacy of beating heart surgery in patients with complex coronary artery disease.
Summary:
- A 7-year study of 100 patients undergoing first-time OPCAB demonstrated favorable postoperative results.
- Key outcomes included low rates of inotrope use (42%), atrial fibrillation (9.4%), and transfusion (27.3%).
- The majority of patients (94.7%) were extubated within 48 hours, with a hospital mortality rate of 10.5%.
Impact:
- Off-pump CABG provides good immediate results, even for patients with multi-vessel disease and those considered high-risk.
- This approach may offer a safer alternative to traditional CABG with cardiopulmonary bypass.
- The findings support the use of OPCAB in selected patient populations.
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