Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

Modeling in Therapy

Modeling in Therapy

Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...

Operant Conditioning Intervention

Operant Conditioning Intervention

Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...

Behavior Modification

Behavior Modification

Behavioral approaches have often been criticized for ignoring mental processes and focusing solely on observable behavior. However, these approaches provide an optimistic perspective for individuals seeking to change their behaviors. Rather than concentrating on intrinsic personality traits, behavioral approaches suggest that even longstanding habits can be modified by changing the reward contingencies that maintain them.
A real-world application of operant conditioning principles is applied...

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.

Personality Disorders: Dependent and Obsessive-Compulsive

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Deleterious coding variation associated with autism is shared across ancestries.

Nature medicine·2026

Same author

Maternal Serotonin Levels and Neurodevelopmental Severity in Autistic Children: A Partial Replication and Extension.

JAACAP open·2025

Same author

Analyses of GWAS and Sub-Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025

Same author

<i>de novo KDM5B</i> Mutation in a Patient with Autism Spectrum Disorder and Obsessive-Compulsive Disorder: Case Report.

Journal of mood and anxiety disorders·2025

Same author

Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.

Nature genetics·2025

Same author

Deleterious coding variation associated with autism is consistent across populations, as exemplified by admixed Latin American populations.

medRxiv : the preprint server for health sciences·2025

Search research articles

Related Experiment Video

Updated: May 13, 2026

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Published on: September 6, 2024

Reduced behavioral flexibility in autism spectrum disorders.

Anna-Maria D'Cruz¹, Michael E Ragozzino, Matthew W Mosconi

¹Department of Psychology, University of Illinois, Chicago, Illinois, USA.

Neuropsychology

|March 27, 2013

Summary

This summary is machine-generated.

Individuals with autism spectrum disorder (ASD) show deficits in flexible choice behavior, particularly in adapting to changing rules. Restricted and repetitive behaviors in ASD are linked to these neurocognitive impairments.

More Related Videos

Operant Procedures for Assessing Behavioral Flexibility in Rats

Operant Procedures for Assessing Behavioral Flexibility in Rats

Published on: February 15, 2015

Strategies for Assessing Autistic-Like Behaviors in Mice

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Related Experiment Videos

Last Updated: May 13, 2026

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Published on: September 6, 2024

Operant Procedures for Assessing Behavioral Flexibility in Rats

Operant Procedures for Assessing Behavioral Flexibility in Rats

Published on: February 15, 2015

Strategies for Assessing Autistic-Like Behaviors in Mice

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Area of Science:

Neuroscience
Psychology
Developmental Disorders

Background:

Autism spectrum disorder (ASD) is characterized by restricted and repetitive behaviors and a need for consistency.
The relationship between these behavioral traits and underlying neuropsychological impairments in behavioral flexibility is not fully understood.

Purpose of the Study:

To investigate behavioral flexibility in individuals with ASD using a probabilistic reversal learning task.
To determine if deficits in behavioral flexibility are associated with restricted and repetitive behaviors in ASD.

Main Methods:

Forty-one individuals with ASD and 37 controls completed a reversal learning task assessing acquisition and reversal phases.
Feedback was provided on an 80:20 probabilistic schedule during the task.

Main Results:

Participants with ASD and controls performed similarly during the acquisition phase.
At reversal, individuals with ASD showed increased regressive errors, reverting to previously learned responses.
Regressive errors positively correlated with the severity of restricted and repetitive behaviors in ASD.

Conclusions:

Restricted and repetitive behaviors in ASD are associated with neurocognitive deficits in flexible choice behavior.
Alterations in frontostriatal circuitry, which supports flexibility, may underlie behavioral rigidity in ASD.
This circuitry represents a potential target for therapeutic interventions in ASD.