[The characteristics of the changes in the aortic endothelium of old rabbits administered adrenaline]

The effect of sharp increase of arterial pressure and blood adrenalin content on the vascular endothelium increases with age. Structural disorders and disturbances in permeability of aortic endothelium after 30-minute adrenalin infusion are more marked in old rabbits. This may be among the factors which induce intensified development of preatherosclerotic changes in the vessels.