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Updated: May 13, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
[Pulmonary embolism and pregnancy]
L Lonjaret1, O Lairez, V Minville
1EA MATN 4564 IFR 150, département d'anesthésie et de réanimation, hôpital Purpan, CHU de Toulouse, place du Docteur-Baylac, 31059 Toulouse cedex 9, France.
Pulmonary embolism (PE) in pregnancy requires prompt diagnosis, often using Doppler ultrasound. Treatment typically involves low molecular weight heparin, with other options available for complex cases.
Area of Science:
- Obstetrics and Gynecology
- Cardiology
- Radiology
Context:
- Pulmonary embolism (PE) is a significant cause of maternal mortality globally.
- Pregnancy presents unique challenges for diagnosing and managing PE due to non-specific symptoms and radiation concerns.
- Existing guidelines for PE management require updates to reflect current knowledge.
Purpose:
- To provide an updated review of diagnostic and therapeutic strategies for pulmonary embolism during pregnancy.
- To consolidate current evidence on the management of pregnant patients with PE.
- To inform clinical practice regarding PE in pregnancy.
Summary:
- Diagnostic approaches prioritize ultrasound Doppler to minimize radiation exposure to mother and fetus.
- Low molecular weight heparin is the recommended anticoagulant therapy for PE in pregnancy.
- Advanced interventions like temporary vena cava filters and thrombolysis are reserved for specific, high-risk situations.
Impact:
- Improved diagnostic accuracy and reduced radiation exposure in pregnant patients with suspected PE.
- Standardized and effective treatment protocols for PE in pregnancy, potentially reducing maternal mortality.
- Enhanced understanding of alternative treatment options for complicated PE cases in pregnant individuals.
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