Related Experiment Video
Updated: May 13, 2026

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Parry Romberg syndrome associated with chronic facial pain
Gloria Dalla Costa1, Bruno Colombo, Dacia Dalla Libera
1Department of Neurology, San Raffaele Scientific Institute, via Olgettina 48, 20132 Milan, Italy. gloria.dallacosta@gmail.com
Abstract:
Parry Romberg Syndrome (PRS) is a rare condition of unknown cause and pathophysiology. It is characterized by progressive facial hemiatrophy, and neurological abnormalities are found in 20% of cases. We describe a 50-year-old woman with PRS and severe neurological involvement (lateralised epileptic seizure activity and facial pain refractory to medication). Pain intensity and frequency was reduced and control of epileptic crises was improved using levetiracetam as an additional therapy. In previous published cases associated with facial pain, the most frequent diagnoses were migraine and trigeminal neuralgia. Our findings suggest that in this patient PRS-related persistent pain has peculiar features possibly attributed to the underlying musculoskeletal abnormalities.
Related Concept Videos
Prosopagnosia
REM Sleep Behavior Disorder
RBD is significantly associated with...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Respiratory Failure-III
Rheumatic Heart Disease I: Introduction
