Related Experiment Video
Updated: May 13, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
Ultrasound-guided root/trunk (interscalene) block for hand and forearm anesthesia
Sarah J Madison1, Julie Humsi, Vanessa J Loland
1University California, San Diego, San Diego, CA, USA.
The interscalene brachial plexus block is often used for shoulder surgery but infrequently provides anesthesia to the hand and forearm. This study found that this block technique does not reliably achieve surgical anesthesia in the hand and forearm.
Area of Science:
- Anesthesiology
- Regional Anesthesia
- Ultrasound-Guided Procedures
Background:
- The anterolateral interscalene block is a common technique for shoulder surgery.
- Historically, this block has shown limited success in providing anesthesia to the hand and forearm.
- The efficacy of targeting the seventh cervical root or inferior trunk for hand and forearm anesthesia remains unclear.
Purpose of the Study:
- To evaluate the effectiveness of an ultrasound-guided interscalene brachial plexus block in achieving surgical anesthesia of the hand and forearm.
- To determine if anesthetic deposition near the deepest brachial plexus roots/trunks reliably anesthetizes the hand and forearm.
Main Methods:
- Ultrasound guidance and a posterior approach were used to position a needle between the deepest and next-deepest brachial plexus roots/trunks.
- Mepivacaine (1.5%) was injected, and grip strength and cutaneous electrical current tolerance were measured for 30 minutes.
- The primary endpoint was at least 90% decrease in grip strength and hand/forearm anesthesia within 30 minutes.
Main Results:
- All 55 subjects achieved shoulder block.
- Only 15% (5 of 33) of subjects demonstrated surgical block of the hand and forearm within 30 minutes.
- Block failures were primarily due to inadequate anesthesia in the ulnar, median, and radial nerve distributions.
Conclusions:
- The interscalene brachial plexus block, as performed in this study, does not reliably provide surgical anesthesia to the hand and forearm.
- The findings do not support the hypothesis that this technique is equivalent to other brachial plexus block approaches for hand and forearm anesthesia.
Related Concept Videos
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Clinical Application as Spinal Anesthesia
Arteries of the Upper Limbs
Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions
Although all competitive neuromuscular blockers are designed...
Depolarizing Blockers: Pharmocokinetics

