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Updated: May 12, 2026

Quantification of Bacterial Histidine Kinase Autophosphorylation Using a Nitrocellulose Binding Assay
Published on: January 11, 2017
A sensitive SERS assay of L-histidine via a DNAzyme-activated target recycling cascade amplification strategy
Sujuan Ye1, Yuanyuan Guo, Jie Xiao
1Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
Abstract:
A novel surface-enhanced Raman scattering (SERS) method is demonstrated to detect L-histidine based on DNAzyme which can specifically recognize L-histidine. Through a target recycling cascade amplification strategy, the DNAzyme-based SERS sensing system affords very high sensitivity for L-histidine with a detection limit of 0.56 nM.
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