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Updated: May 12, 2026

A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering
05:18

A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering

Published on: December 7, 2016

Factors affecting hemoglobin measurement.

Lauren Berkow1

  • 1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, 600 N. Wolfe St., Meyer 8-134, Baltimore, MD, 21287, USA, lberkow1@jhmi.edu.

Journal of Clinical Monitoring and Computing
|March 27, 2013
PubMed
Summary
This summary is machine-generated.

Standard hemoglobin measurements can be inaccurate due to various factors. This review examines physiological influences and technical variations affecting hemoglobin testing reliability.

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Area of Science:

  • Clinical Chemistry
  • Hematology
  • Laboratory Medicine

Background:

  • Standard laboratory measurements for hemoglobin are critical for diagnosing and monitoring various medical conditions.
  • Existing literature indicates significant variability and potential inaccuracies in current hemoglobin testing methods.

Purpose of the Study:

  • To review the literature concerning factors affecting hemoglobin measurements.
  • To discuss physiological influences on hemoglobin levels.
  • To analyze technical aspects and variability of hemoglobin measurement methodologies.

Main Methods:

  • Literature review of scientific articles and clinical studies.
  • Analysis of physiological factors impacting hemoglobin concentration.
  • Evaluation of technical parameters and inter-method variability in hemoglobin assays.

Main Results:

  • Hemoglobin measurements are susceptible to numerous factors influencing accuracy and reliability.
  • Physiological variations can alter "true" hemoglobin values.
  • Technical aspects and diverse methodologies contribute to measurement variability.

Conclusions:

  • Accurate hemoglobin measurement requires understanding both physiological and technical variables.
  • Awareness of influencing factors is crucial for reliable clinical interpretation of hemoglobin results.
  • Further standardization or method-specific considerations may be needed for improved hemoglobin testing.