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Updated: May 12, 2026

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

Malignant biliary obstructions: can we predict immediate postprocedural cholangitis after percutaneous biliary

Shin Ahn¹, Yoon-Seon Lee, Kyung Soo Lim

¹Department of Emergency Medicine, Cancer Emergency Room, Asan Medical Center, University of Ulsan, College of Medicine, 388-1, Pungnap-dong, Songpa-gu, Seoul, 138-736, South Korea. ans1023@gmail.com

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer

|March 27, 2013

Summary

Immediate cholangitis is a common complication following percutaneous transhepatic biliary drainage (PTBD). History of cholangitis, recent biliary drainage, high CRP, and low albumin predict this risk in patients with malignant biliary obstruction.

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Area of Science:

Interventional Radiology
Gastroenterology
Oncology

Background:

Percutaneous transhepatic biliary drainage (PTBD) is a key procedure for managing malignant biliary obstructions.
Immediate cholangitis is a significant complication following PTBD, impacting patient outcomes.

Purpose of the Study:

To identify predictive factors for immediate cholangitis after PTBD in patients with malignant biliary obstruction.

Main Methods:

Retrospective analysis of 409 patients undergoing PTBD for malignant biliary obstruction.
Logistic regression analysis to determine factors associated with cholangitis developing within 24 hours of PTBD.

Main Results:

Immediate cholangitis occurred in 25.9% of patients.
Predictive factors included prior cholangitis, recent biliary drainage, elevated CRP (≥ 5 mg/dL), and low serum albumin (< 3 g/dL).

Conclusions:

Cholangitis is a frequent complication post-PTBD.
Prophylactic antibiotics are recommended prior to drainage.
Identifying high-risk patients can improve post-PTBD monitoring and safety.