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Poststreptococcal syndrome mimicking conjunctival lymphoma
Iwona Rospond-Kubiak1, Agata Brązert, Jarosław Kocięcki
1Department of Ophthalmology, Poznań University of Medical Sciences, 1/2 Długa St., Poznań 61-848, Poland. iwona.rospond-kubiak@wp.pl
BMC Infectious Diseases
|March 28, 2013
Summary
This study reports the first known case of conjunctival lesions in poststreptococcal syndrome (PSS) caused by group A streptococci. Treatment with penicillin led to complete regression of these rare conjunctival manifestations.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Rheumatology
Background:
- Poststreptococcal syndrome (PSS) can follow group A streptococci (GAS) infections.
- While poststreptococcal uveitis is documented, conjunctival involvement has not been previously reported.
- This study aims to describe a unique case of conjunctival lesions mimicking lymphoma.
Observation:
- A 19-year-old female presented with nodular conjunctival infiltrates after a respiratory infection and tonsillectomy.
- Initial histopathology suggested lymphocyte proliferation, and flow cytometry ruled out monoclonal B-cell proliferation.
- Conjunctival lesions resolved completely following benzyl penicillin treatment for elevated antistreptolysin O (ASO) titers.
Findings:
- The conjunctival lesions in this case are believed to be a manifestation of PSS.
- This represents the first reported instance of conjunctival involvement in PSS associated with GAS.
Implications:
- This case expands the spectrum of ocular manifestations of PSS.
- It highlights the importance of considering PSS in the differential diagnosis of conjunctival lesions, especially after GAS infection.
- Prompt diagnosis and treatment of PSS may prevent persistent or severe ocular complications.
