Periprosthetic joint infection: Current concept

Vinay K Aggarwal1, Mohammad R Rasouli, Javad Parvizi

  • 1Department of Adult Reconstruction Surgery, Rothman Institute of Orthopaedics, Thomas Jefferson University, 925 Chestnut Street, Philadelphia, PA 19107, USA.

Insights

Diagnosing and treating periprosthetic joint infection (PJI) after total joint arthroplasty (TJA) is complex. This review covers current challenges and recent advances in PJI diagnosis and management.

Area of Science:

  • Orthopedic surgery
  • Infectious diseases
  • Biomedical engineering

Background:

  • Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty (TJA).
  • Accurate diagnosis of PJI is challenging due to the lack of a gold standard, complicating the differentiation between septic and aseptic joint failures.
  • Optimal treatment strategies for PJI remain a subject of significant debate and international variation.

Purpose of the Study:

  • To review the current diagnostic methods for PJI.
  • To discuss the various management strategies for PJI.
  • To highlight recent advancements in the field of PJI diagnosis and treatment.

Main Methods:

  • Literature review of diagnostic criteria for PJI.
  • Analysis of current surgical and non-surgical treatment options for PJI.
  • Examination of recent research and technological advancements relevant to PJI.

Main Results:

  • No single diagnostic test is universally accepted for PJI.
  • Treatment decisions for PJI involve complex considerations with varied international approaches.
  • Ongoing research is exploring novel diagnostic tools and therapeutic interventions for PJI.

Conclusions:

  • Effective diagnosis and management of PJI remain critical challenges in orthopedic surgery.
  • Further research and standardization of diagnostic and treatment protocols are needed to improve patient outcomes for PJI.
  • Recent advances offer promise for more accurate PJI diagnosis and tailored treatment strategies.

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