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Updated: May 12, 2026

An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
Case report: squamous cell carcinoma of the urinary bladder in a horse
Alanna J Zantingh1, Earl M Gaughan, Fairfield T Bain
1Littleton Equine Medical Center, Colorado, USA.
Abstract:
A 14-year-old Hanoverian gelding was evaluated after a 10-week history of occasional straining during urination and dark red urine production after exercise. Physical examination findings were within normal limits. After 2 weeks of clinical signs, ultrasonography had found no abnormalities in the kidneys or bladder. A freely voided urine sample revealed an elevated protein concentration (500 mg/dL; reference range: <100 mg/dL) and few red blood cells. Vitamin C supplementation was suggested to acidify the urine, as was provision of a salt block to encourage water intake.
