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Updated: May 12, 2026
04:30
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Coronary stents: historical development, current status and future directions
Javaid Iqbal1, Julian Gunn, Patrick W Serruys
1Thorax Centre, Erasmus Medical Centre, Rotterdam, The Netherlands. p.w.j.c.serruys@erasmus.nl
British Medical Bulletin
|March 28, 2013
Summary
Coronary artery stenting is the preferred treatment for angioplasty, with drug-eluting stents reducing restenosis but posing a risk of late stent thrombosis. Dual anti-platelet therapy is recommended, though optimal duration remains debated.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Biomaterials Science
Background:
- Coronary angioplasty with stenting has transformed coronary artery disease management.
- This review details the historical evolution, current practices, and future prospects of coronary stenting.
Purpose of the Study:
- To provide a comprehensive overview of coronary angioplasty and stenting.
- To review contemporary stent technologies, clinical recommendations, and ongoing research.
Main Methods:
- A literature review of coronary stents was conducted using PubMed.
- Data synthesis on stent efficacy, safety, and future directions.
Main Results:
- Coronary artery stenting is the primary treatment for angioplasty.
- Drug-eluting stents minimize restenosis but carry a risk of late stent thrombosis.
- Dual anti-platelet therapy is standard, but its duration is debated.
Conclusions:
- Ongoing research focuses on advanced stent platforms, biocompatible materials, and novel anti-thrombotic/anti-proliferative agents.
- Development of pro-healing stents and bioresorbable scaffolds is a key area for future research.
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