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Updated: May 12, 2026

Clinical Assessment of Spatiotemporal Gait Parameters in Patients and Older Adults

Clinical Assessment of Spatiotemporal Gait Parameters in Patients and Older Adults

Published on: November 7, 2014

Gait variability and multiple sclerosis.

Michael J Socie¹, Jacob J Sosnoff

¹Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Multiple Sclerosis International

|March 28, 2013

Summary

This summary is machine-generated.

People with multiple sclerosis (MS) exhibit greater gait variability, indicating poorer walking function. Factors like disability and fatigue influence this variability, necessitating further research into its underlying causes and clinical significance.

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Area of Science:

Neurology
Biomechanics
Rehabilitation Science

Background:

Gait variability, or fluctuations during walking, is a key indicator of walking function.
Increased gait variability is linked to adverse outcomes, including falls.
Individuals with multiple sclerosis (MS) demonstrate significantly higher gait variability than healthy controls.

Purpose of the Study:

To review current research on gait variability in persons with MS.
To identify factors associated with increased gait variability in MS.
To highlight areas for future investigation in MS gait research.

Main Methods:

Literature review of studies investigating gait variability in multiple sclerosis.
Analysis of factors influencing gait variability, such as disability level, assistive device use, attention, and fatigue.
Synthesis of findings to understand the current state of knowledge.

Main Results:

Persons with MS consistently show greater gait variability compared to controls.
Disability level, use of assistive devices, attentional demands, and fatigue are associated with gait variability in MS.
The precise mechanisms driving increased gait variability in MS remain unclear.

Conclusions:

Gait variability is a significant marker of impaired walking function in MS.
Understanding the factors influencing gait variability is crucial for managing mobility in MS.
Future research should explore the temporal dynamics, clinical impact, and mechanisms of gait variability in MS.