Related Experiment Video
Updated: May 12, 2026

07:30
Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Isolated brainstem involvement in a patient with hypertensive encephalopathy
1Department of Neurology and Neurophysiology, Hamad Medical Corporation, Doha, Qatar.
Case Reports in Neurological Medicine
|March 28, 2013
Summary
Hypertensive encephalopathy can affect the brainstem, causing symptoms. Promptly treating high blood pressure is crucial for recovery and preventing severe complications.
Area of Science:
- Neurology
- Radiology
- Nephrology
Background:
- Hypertensive encephalopathy typically involves parietooccipital vasogenic edema.
- Brainstem edema in hypertensive encephalopathy is usually secondary and asymptomatic.
Purpose of the Study:
- To report a case of hypertensive encephalopathy with isolated brainstem involvement.
- To highlight the importance of prompt diagnosis and treatment.
Main Methods:
- Case report of a patient with hypertensive encephalopathy.
- Magnetic resonance imaging (MRI) to assess brainstem edema.
- Monitoring of clinical and radiological changes after hypertension treatment.
Main Results:
- The patient presented with isolated brainstem edema on MRI.
- Rapid treatment of hypertension led to clinical and radiological improvement.
Conclusions:
- Hypertensive encephalopathy can manifest with isolated brainstem edema.
- Aggressive management of hypertension is vital for edema resolution and preventing progression.
Related Concept Videos
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Hepatic Encephalopathy
DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...
Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Encephalitis ll: Pathophysiology
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
