[Evaluation of the practice of transfusion in the anemia in preterm infants]

S Elguazzar1, A Mdaghri Alaoui, A Thimou Izgua

  • 1Service de Néonatologie, Pédiatrie V, Hôpital d'Enfants, Faculté de Médecine et Pharmacie, Université Mohammed V-Souissi, Rabat, Maroc.

Insights

Early anemia in preterm infants often leads to erythrocyte transfusions. This study found transfused infants were more premature, had lower birth weights, and longer hospital stays, indicating a need for preventive measures.

Area of Science:

  • Neonatal Medicine
  • Pediatric Hematology
  • Clinical Practice Evaluation

Background:

  • Early anemia is common in preterm infants.
  • Erythrocyte transfusions are a frequent remedy for anemia in neonates.
  • Transfusion criteria vary significantly between neonatal centers.

Purpose of the Study:

  • To evaluate transfusion practices for anemia in preterm infants at a specific neonatal service.
  • To analyze the clinical and biological indications for blood transfusions in this population.

Main Methods:

  • A descriptive study of 113 preterm infants (<37 weeks gestation) hospitalized in 2006.
  • Data collected included gestational age, birth weight, hemoglobin, and hematocrit levels.
  • Comparison between transfused (n=65) and non-transfused (n=48) groups using statistical tests (Chi-squared, t-Student).

Main Results:

  • 57.5% of preterm infants received transfusions.
  • Transfused infants were significantly more premature, had lower birth weights, longer hospitalizations, and higher rates of nosocomial infections and postnatal bleeding.
  • Transfused infants had lower initial hemoglobin and hematocrit levels compared to non-transfused infants.

Conclusions:

  • Blood transfusion use is frequent in this neonatal setting.
  • Preventive strategies are necessary to reduce the incidence of transfusions.
  • Further research into optimizing transfusion criteria and anemia management in preterm infants is warranted.
Abstract