Related Experiment Video
Updated: May 12, 2026

Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
Published on: September 18, 2016
[Inflammatory bowel diseases: experiencing illness, therapy and care]
Horst Rettke1, Diana Staudacher, Silvia Schmid-Büchi
1Zentrum Klinische Pflegewissenschaft, UniversitätsSpital Zürich. horst.rettke@usz.ch
Abstract:
People affected by Crohn's disease or ulcerative colitis experience a high level of suffering. A new generation of anti-tumour necrosis factor-α agents can alleviate the burden of symptoms considerably. In order to develop a need-centred care programme for this patient group, we conducted problem-centred interviews with nine patients about their experience of the disease, the therapy and the quality of nursing care. The evaluation was based on qualitative content analysis. Patients' statements revealed three general categories: (1) "the never ending story" of a life with IBD, (2) "the sudden change" due to successful therapy and (3) "the narrow path" of a new stage of life: the disease no longer dominated daily life. The results emphasise the necessity of specific care for this patient group in order to perceptibly enhance their self-management and quality of life. The study illuminates a developing field of ambulant nursing care, based on the knowledge of patients' needs in the context of a chronic disease characterised by an unpredictable and irregular course.
Related Concept Videos
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease I: Introduction

