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Updated: May 12, 2026
06:57
Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
Published on: September 18, 2016
[Inflammatory bowel diseases: experiencing illness, therapy and care]
Horst Rettke1, Diana Staudacher, Silvia Schmid-Büchi
1Zentrum Klinische Pflegewissenschaft, UniversitätsSpital Zürich. horst.rettke@usz.ch
Pflege
|March 29, 2013
Summary
Patients with inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, benefit significantly from new anti-tumour necrosis factor-α therapies. These treatments improve quality of life and self-management, necessitating tailored nursing care programs.
Area of Science:
- Gastroenterology and Hepatology
- Immunology
- Nursing Science
Context:
- Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, significantly impacts patients' quality of life.
- Emerging anti-tumour necrosis factor-α (anti-TNFα) therapies offer substantial symptom relief.
- Understanding patient experiences is crucial for developing effective, patient-centered care.
Purpose:
- To explore the lived experiences of patients with IBD undergoing anti-TNFα therapy.
- To identify patient needs for developing a need-centered care program.
- To inform the development of specialized ambulant nursing care for IBD patients.
Summary:
- Qualitative content analysis of interviews with nine IBD patients revealed three key themes: the chronic nature of the disease, the transformative impact of successful anti-TNFα therapy, and adapting to a life where the disease is no longer dominant.
- Patients' narratives highlight the profound shift in daily living and self-perception following effective treatment.
- The study underscores the unpredictable and irregular course of IBD and its management.
Impact:
- The findings emphasize the necessity of specialized nursing care to enhance patient self-management and quality of life in IBD.
- This research illuminates the evolving landscape of ambulant nursing care for chronic conditions.
- Results provide a foundation for improving healthcare delivery and patient support in gastroenterology.
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