Related Experiment Video
Updated: May 12, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Recent developments in design and synthesis of bicyclic azasugars, carbasugars and related molecules as glycosidase
Rima Lahiri1, Alafia A Ansari, Yashwant D Vankar
1Department of Chemistry, Indian Institute of Technology, Kanpur-208016, India.
Abstract:
The importance of glycosidase inhibitors and especially the bicyclic molecules has led to design and assessment of many analogs of naturally occurring molecules. This review focuses on the synthesis and enzyme inhibitions of a few selected (synthetic or non-naturally occurring) molecules that have been reported in the last decade, which allow one to draw some connection between varying the structural features and their effect on glycosidase inhibitions. It is expected that further improvements based on these features could lead to improved inhibitors.
More Related Videos
Related Concept Videos
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
Acarbose and miglitol are typically...
Oral Hypoglycemic Agents: Sulfonylureas
Biosynthesis of Polysaccharides
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Oral Hypoglycemic Agents: Biguanides and Glitazones
Protein Glycosylation
Glycosylation occurs in...

