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The prevalence of allergic fungal rhinosinusitis in sinonasal polyposis

Mehdi Bakhshaee1, Mohammad Fereidouni, Morteza Nourollahian Mohajer

  • 1Ear, Nose and Throat Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|March 29, 2013
PubMed

Insights

Allergic fungal sinusitis (AFS) affects 9.45% of patients with nasal polyposis in Northeast Iran. This study identified Aspergillus and Alternaria fungi as common causes in patients with higher IgE levels.

Area of Science:

  • Otolaryngology
  • Allergy and Immunology
  • Mycology

Background:

  • Allergic fungal sinusitis (AFS) is a noninvasive fungal rhinosinusitis.
  • Its prevalence varies globally, impacting 6-9% of surgical rhinosinusitis cases.
  • Diverse fungal species contribute to AFS, with regional incidence differences.

Purpose of the Study:

  • To determine the prevalence of AFS in rhinosinusitis patients in Northeast Iran.
  • To identify common fungal culprits and associated allergens in this region.

Main Methods:

  • A prospective cross-sectional study involving 127 patients with sinonasal polyposis undergoing surgery.
  • Evaluations included sinonasal CT scans, allergen prick tests, serum IgE levels, and fungal cultures of allergic mucin.
  • Data analysis utilized SPSS version 13.0.

Main Results:

  • The prevalence of AFS was found to be 9.45% among the studied patients.
  • Aspergillus (9 cases) and Alternaria (3 cases) were the most frequently cultured fungi.
  • Allergen prick tests were positive in 22.05% of patients, with weed being the most common allergen.
  • AFS patients exhibited significantly higher total IgE levels.

Conclusions:

  • The prevalence of allergic fungal sinusitis in Northeast Iran is 9.45% among patients with nasal polyposis.
  • Fungal identification and allergen testing are crucial for diagnosing AFS.
  • Elevated IgE levels are indicative of AFS in this patient population.

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