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Updated: May 12, 2026
Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
Published on: February 9, 2021
Thienopyrrole-expanded BODIPY as a potential NIR photosensitizer for photodynamic therapy
Yongchao Yang1, Qiuli Guo, Huachao Chen
1State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing 210093, PR China.
Abstract:
The synthesis and characterization of a highly photostable bromo-substituted BODIPY dye (I) fused-ring-expanded with thienopyrrole moieties is reported. The results of MTT assays and flow cytometric analyses in living HeLa cells demonstrate that I has a high singlet oxygen quantum yield (ΦΔ = 0.63) and exhibits photocytotoxicity upon irradiation in the NIR region making it potentially suitable for use in PDT.
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