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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: May 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Published on: June 2, 2014

Functional imaging in chronic migraine.

Farooq H Maniyar1, Peter J Goadsby

  • 1Headache Group-Department of Neurology, University of California, San Francisco, 1701 Divisadero St, San Francisco, CA 94115, USA. farooq_maniyar@hotmail.com

Current Pain and Headache Reports
|March 29, 2013
PubMed
Summary
This summary is machine-generated.

Chronic migraine progression is not fully understood. Recent studies using functional neuroimaging reveal brain changes in areas like the brainstem and basal ganglia associated with increased migraine frequency.

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Area of Science:

  • Neuroscience
  • Neurology
  • Medical Imaging

Background:

  • Chronic migraine is a prevalent neurological disorder causing significant disability and economic burden.
  • The underlying mechanisms driving the transition from episodic to chronic migraine remain unclear.
  • Understanding these mechanisms is crucial for developing effective treatments.

Purpose of the Study:

  • To review recent research on chronic migraine and the increasing frequency of migraine attacks.
  • To explore the utility of functional neuroimaging in understanding migraine pathophysiology.
  • To identify brain regions associated with migraine chronification.

Main Methods:

  • Review of recent scientific literature focusing on chronic migraine and migraine attack frequency.
  • Analysis of studies employing functional neuroimaging techniques.
  • Correlation of neuroimaging findings with changes in brain activity and blood flow.

Main Results:

  • Increasing frequency of migraine attacks is linked to alterations in specific brain regions.
  • Key areas affected include brainstem nuclei, basal ganglia, and cortical regions involved in pain processing.
  • Functional neuroimaging provides insights into the neural correlates of migraine progression.

Conclusions:

  • Migraine chronification involves changes in distributed neural networks.
  • Functional neuroimaging is a valuable tool for investigating the neurobiology of chronic migraine.
  • Further research is needed to elucidate the precise mechanisms and inform therapeutic strategies.