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Studies on the relationship between the equilibrium curve of oxyhemoglobin and 2,3-diphosphoglycerate in open-heart
Canadian Journal of Surgery. Journal Canadien De Chirurgie
|January 1, 1975
Abstract:
The relationship between decreased oxygen affinity of hemoglobin and intraerythrocyte 2,3-diphosphoglycerate (2,3 DPG) concentration was confirmed and its existence during the period of open-heart surgery was demonstrated. It is suggested that the trauma sustained by the erythrocytes during their extracorporeal circulation is responsible, in large measure, for the decrease in 2,3 DPG concentration.