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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Central toxic keratopathy: a clinical case series
José Francisco Marí Cotino1, Mayerling Mercedes Suriano, Rosario Inés De La Cruz Aguiló
1Department of Ophthalmology Service, Hospital Clínico Universitario de Valencia, Valencia, Spain.
The British Journal of Ophthalmology
|March 29, 2013
Summary
Central toxic keratopathy (CTK) after laser eye surgery (LASIK) was described in 12 eyes. A potential cause identified was a change in surgical glove brand, suggesting a link to glove substances.
Area of Science:
- Ophthalmology
- Surgical Complications
Background:
- Central toxic keratopathy (CTK) is a rare complication following refractive surgery.
- The etiology of CTK remains incompletely understood, necessitating further investigation.
Purpose of the Study:
- To clinically describe a case series of central toxic keratopathy (CTK).
- To investigate a potential etiology for CTK following laser-assisted in situ keratomileusis (LASIK).
Main Methods:
- Retrospective observational case series.
- Inclusion of 12 eyes diagnosed with CTK post-LASIK.
- Analysis of clinical presentation and outcomes.
Main Results:
- 12 out of 28 eyes developed CTK within 4 days of LASIK.
- CTK resolution occurred between 1 to 9 months (average 4.6 months).
- CTK onset coincided with a change in surgical glove brand; no further cases occurred after replacement.
Conclusions:
- Clinical findings of CTK are well-defined, but its origin is unknown.
- CTK appears to not require specific treatment.
- A possible link between surgical glove substances and CTK development is suggested, warranting further research.
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