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Updated: May 12, 2026

A Contusion Model of Severe Spinal Cord Injury in Rats
Published on: August 17, 2013
A silent acute abdomen in a patient with spinal cord injury
Rishi Malhotra1, Gerard Ee, Si Ying Pang
1Department of Orthopaedics, National University Hospital, Singapore.
Abstract:
A 52-year-old man with cervical spondylosis sustained a hyperextension injury to the neck and subsequently developed central cord syndrome after 2 weeks. The diagnosis was confirmed clinically and on MRI. During the admission he was febrile from Streptococcus anginosus bacteraemia from a gum infection and was started on penicillin. This resulted in pseudomembranous colitis with abdominal distension and bloody diarrhoea but a lack of expected abdominal complaints. Unfortunately his neurology deteriorated and a repeat MRI showed a discitis at C5-C7 which required a 2-level discectomy, debridement and instrumented fusion. Owing to his spinal cord injury, an abdominal perforation was initially missed owing to the lack of clinical features of an acute abdomen. He underwent a right hemi-colectomy for ascending colon perforation and eventually made a good recovery and was discharged to a spinal rehabilitation unit. By one year follow-up he had returned to full neurological function.
Insights
A man with cervical spondylosis developed central cord syndrome after a neck injury. Complications included bacterial infection, colitis, and abdominal perforation, but he achieved full neurological recovery.
Area of Science:
- Neurology
- Infectious Disease
- Spinal Surgery
Background:
- Cervical spondylosis predisposes individuals to neurological deficits following hyperextension injuries.
- Central cord syndrome is a distinct neurological outcome following spinal trauma.
Observation:
- A patient with cervical spondylosis developed central cord syndrome post-injury.
- He experienced Streptococcus anginosus bacteremia, leading to pseudomembranous colitis.
- Neurological deterioration prompted imaging, revealing C5-C7 discitis requiring surgical intervention.
Findings:
- The patient underwent discectomy, debridement, and fusion for C5-C7 discitis.
- An ascending colon perforation, initially masked by spinal cord injury symptoms, necessitated a right hemicolectomy.
- Despite multiple complications, the patient achieved complete neurological recovery within one year.
Implications:
- This case highlights the complex interplay between spinal cord injury and systemic complications.
- It underscores the importance of vigilant diagnosis and management in patients with severe trauma and co-existing infections.
- Successful surgical and medical management can lead to significant neurological recovery even after severe spinal cord injury and associated morbidities.
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