Related Experiment Video
Updated: May 12, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Endovascular management of pulmonary artery stenosis due to tumor compression
Sapan S Desai1, Anahita Dua, Sheila M Coogan
1Department of Cardiothoracic and Vascular Surgery, The University of Texas Medical School at Houston, TX, USA.
Abstract:
A 75-year-old man with invasive thymoma encasing the aortic arch and pulmonary arteries was referred to our institution with a 1-year history of dyspnea and worsening right heart failure. Pulmonary angiogram demonstrated greater than 90% stenosis of the right pulmonary artery. Balloon angioplasty and stent placement were performed with immediate improvement in his shortness of breath and peripheral edema. Improved lung opacification was noted on completion arteriography, and the stents remained patent until the patient expired from complications related to his cancer 2 years later. Pulmonary artery stenting in noncongenital causes of stenosis is a safe and effective therapy.
Related Concept Videos
Aneurysm III: Interprofessional Care
Mitral Stenosis III: Medical Management
Peripheral Artery Disease III: Interprofessional Care
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Aortic Regurgitation III: Medical Management
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
