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Updated: May 12, 2026

10:13
A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies
Published on: November 7, 2015
[Tumor boards: why they are necessary and which structure is needed]
1Abteilung für Allgemeine und Kinderradiologie, Universitätsklinik für Radiodiagnostik - Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich. benjamin.halpern@meduniwien.ac.at
Der Radiologe
|March 30, 2013
Summary
Tumor boards are increasingly vital for managing complex cancer care. Radiologists play a key role in diagnosis and staging, enhancing patient outcomes through multidisciplinary collaboration.
Area of Science:
- Oncology
- Radiology
- Medical Management
Context:
- Increasing complexity in oncologic disease diagnosis and treatment.
- Need for specialized, multidisciplinary patient management.
- Growing role of integrated care teams in clinical practice.
Purpose:
- To review the expanding significance of tumor boards in clinical oncology.
- To highlight the critical contribution of radiology within tumor boards.
- To emphasize the necessity of collaborative approaches for optimal cancer care.
Summary:
- Tumor boards are essential for managing complex oncologic diseases.
- Radiology is central to the diagnostic process, including accurate tumor staging.
- Multidisciplinary teams, including radiologists, are crucial for effective patient management.
Impact:
- Improved diagnostic accuracy and therapeutic planning for cancer patients.
- Enhanced collaboration between oncologists and radiologists.
- Optimized patient management through integrated, expert-driven decision-making.
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The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

