Recent advances in the molecular and genetic understanding of congenital gastrointestinal malformations
Véronique Dauvé1, Valérie A McLin
1Département de Pédiatrie, Faculté de Médecine, Hôpitaux Universitaires de Genève et Université de Genève, Genève, Switzerland. valerie.mclin@hcuge.ch
Journal of Pediatric Gastroenterology and Nutrition
|March 30, 2013
Abstract:
Major developmental paradigms are highly conserved among vertebrates. The contribution of developmental biology to the understanding of human disease and regeneration has soared recently. We review advances in the molecular and genetic understanding of gastrointestinal development using evidence from both mammalian and nonmammalian models. When appropriate, we highlight relevance and applicability to human disease.
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