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Mid-term clinical outcome following endovascular therapy in patients with chronic aortic occlusion
Tomoharu Dohi1, Osamu Iida, Shin Okamoto
1Kansai Rosai Hospital Cardiovascular Center, 3-1-69 Inabaso, Amagasaki, Hyogo, 660-8511, Japan, tomoharu.dohi@gmail.com.
Insights
Endovascular therapy (EVT) with stenting shows promising mid-term durability for chronic aortic occlusion, with 76% primary patency at 36 months. This treatment is a safe alternative to bypass surgery for suitable patients.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Interventions
Background:
- Endovascular therapy (EVT) is common for iliac lesions but not established for aortic occlusion due to long-term outcome uncertainty.
- Stenting offers acceptable patency for iliac lesions, prompting investigation into its use for more complex aortic occlusive disease.
Purpose of the Study:
- To investigate the outcomes of EVT with stenting for chronic aortic occlusion.
- To assess the safety and mid-term durability of EVT in patients with chronic aortic occlusion.
Main Methods:
- Single-center retrospective analysis of a prospectively maintained database.
- Inclusion of 25 patients (24 lesions) with chronic aortic occlusion treated with EVT and stenting between 2005 and 2012.
- Kaplan-Meier analysis used to determine patency rates based on Society for Vascular Surgery criteria.
Main Results:
- All lesions were Trans Atlantic Inter-Society Consensus D type, with a mean length of 145 mm.
- Initial success rate was 96%, with an 8% procedural complication rate.
- At 36 months, primary and secondary patency rates were 76% and 94%, respectively. Five patients experienced restenosis, all managed with reintervention.
Conclusions:
- EVT with stenting is a safe procedure for patients diagnosed with chronic aortic occlusion.
- The procedural morbidity and mid-term durability of EVT for chronic aortic occlusion are comparable to bypass surgery up to 3 years.
Abstract:
Although endovascular therapy (EVT) has been widely used for iliac lesions due to acceptable patency with stenting, EVT has not been established as primary treatment for aortic occlusion, partly because of uncertainty regarding long-term results. The purpose of this study was to investigate outcomes following EVT with stenting for chronic aortic occlusion. This study was a single-center retrospective analysis of a prospectively maintained database. Between September 2005 and May 2012, twenty-four lesions from 25 patients with a clinical diagnosis of chronic aortic occlusion (mean age, 71 years; 80 % male) were treated with EVT with stenting. Kaplan-Meier estimators were used to determine the patency rates according to Society for Vascular Surgery criteria. In results, lesion type was Trans Atlantic Inter-Society Consensus D in all patients. Mean lesion length was 145 mm. Initial success rate and procedural complication rate were 96 % (24/25) and 8 % (2/25), respectively. At 36 months, primary and secondary patency rates were 76 and 94 %, respectively. Restenosis was observed in 5 patients, all of whom underwent reintervention (four successful, one failure and intensity of medical treatment). EVT can be safely done in patients with chronic aortic occlusion. Procedural morbidity and mid-term durability were comparable to those of bypass surgery up to 3 years.
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