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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Published on: April 4, 2012
A pilot study: does obesity begin in the first year of life?
Susan M Ludington-Hoe1, Lisaann S Gittner, Harold S Haller
1Case Western Reserve University, Cleveland, OH, USA.
Aim:
To determine if growth patterns in healthy infants can identify associations with obesity at age 5 years.
Method:
Body mass index growth patterns from birth to 1 year were described for cohorts of children who were classified at 5 years as normal weight (n = 61), overweight (n = 47), obese (n = 41), and morbidly obese (n = 72). A longitudinal analysis of body mass index means based on the age postbirth was conducted and graphed.
Results:
Distinctions in growth patterns were evident before 1 year postbirth. Children who were normal weight at 5 years demonstrated a growth pattern in the first year that differed from children who were overweight, obese, or morbidly obese at 5 years.
Conclusions:
Obesity growth patterns were seen in infancy and are clinically important because identification of infants who do not fit a normal weight pattern can occur and thus guide individualized interventions in the first year postbirth while precursors of later health are still forming.
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