A pilot study: does obesity begin in the first year of life?
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Updated: May 12, 2026

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Published on: April 4, 2012
Susan M Ludington-Hoe1, Lisaann S Gittner, Harold S Haller
1Case Western Reserve University, Cleveland, OH, USA.
Insights
Infant growth patterns in the first year can predict childhood obesity. Identifying abnormal weight gain early allows for timely interventions to promote healthy development and prevent future health issues.
Area of Science:
- Pediatric endocrinology
- Growth and development studies
- Obesity research
Background:
- Childhood obesity is a growing public health concern.
- Early identification of obesity risk factors is crucial for effective intervention.
- Understanding infant growth trajectories may offer insights into later obesity development.
Purpose of the Study:
- To investigate the association between infant body mass index (BMI) growth patterns from birth to 1 year and the development of obesity at age 5 years.
- To determine if early growth patterns can serve as predictive markers for childhood obesity.
Main Methods:
- Longitudinal analysis of BMI growth patterns in healthy infants from birth to 1 year.
- Children were categorized at age 5 years into normal weight, overweight, obese, and morbidly obese groups.
- Statistical analysis of BMI means based on age postbirth.
Main Results:
- Significant distinctions in infant BMI growth patterns were observed before 1 year of age.
- Infants who were normal weight at 5 years exhibited a different growth trajectory in the first year compared to those who became overweight or obese.
- Early growth patterns identified at less than 1 year predicted later weight status at 5 years.
Conclusions:
- Obesity-related growth patterns are detectable in infancy.
- Early identification of abnormal infant growth trajectories is clinically significant.
- Interventions during the first year of life, guided by growth pattern analysis, can address precursors to later obesity and improve long-term health outcomes.
Aim:
To determine if growth patterns in healthy infants can identify associations with obesity at age 5 years.
Method:
Body mass index growth patterns from birth to 1 year were described for cohorts of children who were classified at 5 years as normal weight (n = 61), overweight (n = 47), obese (n = 41), and morbidly obese (n = 72). A longitudinal analysis of body mass index means based on the age postbirth was conducted and graphed.
Results:
Distinctions in growth patterns were evident before 1 year postbirth. Children who were normal weight at 5 years demonstrated a growth pattern in the first year that differed from children who were overweight, obese, or morbidly obese at 5 years.
Conclusions:
Obesity growth patterns were seen in infancy and are clinically important because identification of infants who do not fit a normal weight pattern can occur and thus guide individualized interventions in the first year postbirth while precursors of later health are still forming.
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