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Updated: May 12, 2026

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
Published on: May 6, 2020
[Degenerative osteoarthritis, osteoporosis and fractures: controversies and evidences]
Aina Pagès-Castellà1, Daniel Prieto Alhambra
1Grup de Recerca GREMPAL, Unitat de Suport a la Recerca Barcelona, Institut d'Investigació en Atenció Primària (IDIAP) Jordi Gol, Barcelona, España.
Abstract:
Osteoarthritis and osteoporosis are both common conditions in the elderly but their association has long remained obscure. Recently published studies show that patients with osteoarthritis have higher bone mass but no corresponding decrease in fracture risk. This has been proposed to be due to an increased rate of falls in these patients. Multi-disciplinary interventions, vitamin D supplementation and bisphosphonates can play a role on preventing fractures among osteoarthritis patients, but evidence on their efficacy is scarce and of poor quality.
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