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Updated: May 12, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Various approaches for vascular health in elderly women
Hiromichi Suzuki1, Manami Dogi, Tsuneo Takenaka
1Department of Nephrology, Saitama Medical University, Saitama, Japan. iromichi@saitama-med.ac.jp
Insights
Ambulatory blood pressure monitoring is more accurate than clinic measurements for elderly women. Clinic measurements of pulse wave velocity and central aortic pressure may be unreliable due to white coat or masked hypertension.
Area of Science:
- Cardiology
- Geriatric Medicine
- Hypertension Research
Background:
- Cardiovascular disease is a major health concern for elderly women.
- Traditional clinic blood pressure measurements may not fully capture cardiovascular risk.
- Ambulatory blood pressure monitoring (AMBP) shows promise in predicting cardiovascular outcomes.
Purpose of the Study:
- To evaluate the relationship between various cardiovascular risk factors in elderly women.
- To compare clinic-based measurements with ambulatory monitoring for key cardiovascular parameters.
Main Methods:
- The study involved 24 elderly hypertensive women.
- Data on clinic blood pressure (BP), pulse pressure (PP), pulse wave velocity (PWV), central aortic pressure (CAP), ambulatory systolic blood pressure (AMSBP), and ambulatory central aortic pressure (AMCAP) were collected using BPro.
- Repeated measurements were compared with single clinic readings.
Main Results:
- A significant correlation was observed between ambulatory systolic blood pressure (AMSBP) and ambulatory central aortic pressure (AMCAP).
- No significant correlations were found between repeated measurements and single clinic measurements for PWV and CAP.
- Clinic-based PWV and CAP measurements showed variability compared to ambulatory data.
Conclusions:
- Ambulatory blood pressure monitoring provides a more reliable assessment of cardiovascular parameters in elderly women.
- Clinic measurements of PWV and CAP may be inaccurate in patients with white coat or masked hypertension.
- Further research is needed to validate ambulatory monitoring for cardiovascular risk assessment in this population.
Abstract:
Cardiovascular disease is one of the leading causes of morbidity and mortality in elderly women. Several previous studies evaluated various cardiovascular risk factors, such as brachial blood pressure (BP), systolic blood pressure (SBP), pulse pressure (PP), pulse wave velocity (PWV), central aortic pressure (CAP), and so on. More recently, measurement of ambulatory blood pressure (AMBP) was shown to be superior to clinic measurements in predicting cardiovascular mortality. However, the data are limited concerning the relationship among these variables in elderly women. In the present study, the data for clinic BP including PP, PWV, CAP, and AMSBP and AMCAP obtained using BPro were evaluated in 24 elderly hypertensive women. Although there was a significant correlation between AMSBP and AMCAP, no correlations were found between repeated measured values and values measured in the clinic on one occasion. In conclusion, measuring PWV and CAP in the clinic in patients with white coat hypertension or masked hypertension may not be an accurate way to measure these parameters.
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