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Updated: May 12, 2026

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation
Published on: August 26, 2011
Abnormal fusiform activation during emotional-face encoding assessed with functional magnetic resonance imaging
Nancy E Adleman1, Reilly R Kayser, Aviva K Olsavsky
1Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA. adlemann@mail.nih.gov
None:
This functional magnetic resonance imaging study shows that children and adults with bipolar disorder (BD), compared with healthy subjects, exhibit impaired memory for emotional faces and abnormal fusiform activation during encoding. Fusiform activation abnormalities in BD were correlated with mania severity and may therefore represent a trait and state BD biomarker.
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