Related Experiment Videos
Vitamin K-dependent carboxylase: structural requirements for propeptide activation
A Cheung1, J W Suttie, M Bernatowicz
1Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison 53706.
Biochimica Et Biophysica Acta
|May 31, 1990
Abstract:
The activity of the rat liver vitamin K-dependent gamma-glutamyl carboxylase has been shown to be stimulated by the presence of the free amino terminal 'propeptide' region of the primary gene product of its normal protein substrates. A series of analogs of the human factor X propeptide have been utilized to demonstrate the structure/function relationships important in these interactions.