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Related Experiment Video

Updated: May 12, 2026

Encapsulated Cell Technology for the Delivery of Biologics to the Mouse Eye

Encapsulated Cell Technology for the Delivery of Biologics to the Mouse Eye

Published on: March 30, 2020

Cell-based therapies for ocular inflammation.

John V Forrester¹, Raymond J Steptoe, Izabela P Klaska

¹Immunology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia. j.forrester@abdn.ac.uk

Progress in Retinal and Eye Research

|April 2, 2013

Summary

This summary is machine-generated.

Cell-based therapies show promise for ocular diseases by regenerating tissues or modulating inflammation. Mesenchymal stem cells, for instance, offer potent immunomodulatory effects, expanding therapeutic potential.

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Last Updated: May 12, 2026

Encapsulated Cell Technology for the Delivery of Biologics to the Mouse Eye

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Published on: March 30, 2020

Production of Modified Autologous Conditioned Serum and Ex Vivo Assessment of Its Healing Potential in Murine Corneal Epithelium

Production of Modified Autologous Conditioned Serum and Ex Vivo Assessment of Its Healing Potential in Murine Corneal Epithelium

Published on: March 24, 2023

Area of Science:

Ophthalmology
Regenerative Medicine
Immunology

Background:

Cell plasticity and reprogramming have spurred interest in cell-based therapies for various diseases.
Ocular diseases are a key focus, with perceived lower risks of immune rejection.
Cell therapies target tissue restoration or immunological homeostasis, with functional overlap observed.

Purpose of the Study:

To review recent advancements in cell-based therapies for ocular diseases.
To emphasize applications in ocular inflammatory conditions.
To explore current uses, potential, and limitations of these therapies.

Main Methods:

Literature review of recent studies on cell-based therapies for ocular conditions.
Focus on stem cells (e.g., mesenchymal stem cells) and immune cells.
Analysis of therapeutic strategies for tissue regeneration and immunomodulation.

Main Results:

Stem cells are primarily used for regenerating failing cells and tissues.
Immune cells are explored for modulating ocular inflammation.
Mesenchymal stem cells exhibit significant immunomodulatory properties, bridging regenerative and immunomodulatory applications.

Conclusions:

Cell-based therapies offer diverse approaches for treating ocular diseases.
Significant potential exists for managing ocular inflammatory conditions.
Further research is needed to fully understand and overcome limitations in current applications.