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Neutrophil lymphocyte ratios in stroke subtypes and transient ischemic attack
S Gökhan1, A Ozhasenekler, H Mansur Durgun
1Emergency Service, Diyarbakir Training and Research Hospital, Diyarbakir, Turkey. servan.gokhan@yahoo.com
European Review for Medical and Pharmacological Sciences
|April 2, 2013
Summary
The Neutrophil Lymphocyte Ratio (NLR) is a valuable inflammatory marker for predicting short-term prognosis and in-hospital mortality in stroke patients. Higher NLR levels indicate poorer outcomes in both ischemic and hemorrhagic stroke cases.
Area of Science:
- Neurology
- Inflammation markers
- Cardiovascular research
Background:
- The Neutrophil Lymphocyte Ratio (NLR) is an emerging inflammatory marker with prognostic significance.
- Its utility in emergency department patients with cerebrovascular events requires further investigation.
Purpose of the Study:
- To evaluate the prognostic value of NLR in patients presenting with stroke (ischemic and hemorrhagic) and transient ischemic attack (TIA).
- To assess NLR levels across different cerebrovascular accident types and their correlation with mortality.
Main Methods:
- A cohort of 868 patients presenting to the Emergency Service with cerebrovascular accidents (stroke and TIA) was analyzed.
- Patients were categorized into acute ischemic stroke (AIS), acute hemorrhagic stroke (AHS), and TIA groups.
- Admission NLR levels were compared across these groups and AIS subgroups based on TOAST criteria.
Main Results:
- NLR was significantly higher in non-surviving patients (p < 0.001).
- NLR levels were significantly lower in the TIA group compared to AIS and AHS groups (p < 0.001).
- Among AIS subgroups, significantly higher NLR was observed in patients with great artery atherosclerosis or atherothrombosis (p < 0.001).
Conclusions:
- NLR serves as a simple and accessible marker for predicting short-term prognosis in stroke patients.
- NLR can aid in assessing in-hospital mortality risk for both ischemic and hemorrhagic stroke.
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