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Updated: May 12, 2026

Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
Published on: December 9, 2022
Pseudomyxoma peritonea: uncommon presentation
Vidhyachandra Vijaykumar Gandhi1, Sanjay Nagral
1Jaslok Hospital, Peddar Road 15, Dr G Deshmukh Marg, Mumbai, Maharashtra 400026 India.
Abstract:
Pseudomyxoma peritonei is rare being characterized by intraperitoneal accumulation of mucinous ascites produced by neoplastic cells, mostly originating from a perforated appendiceal adenoma. The clinical presentatation of the disease is variable, and preoperative diagnosis is often difficult. We describe the clinical case of a 60-year-old patient who presentated predominantly with urological symptoms. CECT revealed an appendiceal lesion infiltrating and projecting into the urinary bladder. Surgical cytoreduction was performed and patient remains symptomatically better on follow up.
Insights
Pseudomyxoma peritonei, a rare condition of mucinous ascites, often presents with vague symptoms. This case highlights a patient with predominantly urological issues, emphasizing diagnostic challenges and successful surgical management.
Area of Science:
- Gastroenterology
- Oncology
- Urology
Background:
- Pseudomyxoma peritonei is a rare malignancy characterized by mucinous ascites.
- It typically originates from a perforated appendiceal adenoma.
- Clinical presentation is variable, often leading to diagnostic difficulties.
Purpose of the Study:
- To describe a unique clinical case of pseudomyxoma peritonei.
- To highlight the diagnostic challenges posed by atypical urological symptoms.
- To report the outcome of surgical cytoreduction.
Main Methods:
- Case report of a 60-year-old patient.
- Clinical presentation with predominant urological symptoms.
- Diagnostic imaging including contrast-enhanced computed tomography (CECT).
- Surgical intervention involving cytoreduction.
Main Results:
- CECT revealed an appendiceal lesion infiltrating the urinary bladder.
- Surgical cytoreduction was successfully performed.
- The patient experienced symptomatic improvement post-surgery.
Conclusions:
- Pseudomyxoma peritonei can present with unusual urological symptoms.
- Early diagnosis and surgical intervention are crucial for patient outcomes.
- This case underscores the importance of considering rare diagnoses in complex presentations.
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