Related Experiment Video
Updated: May 12, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
Published on: May 9, 2013
[A case of prolonged hypercapnea after interscalene brachial plexus block]
Yumiko Kohno1, Keiko Koishi, Kazunori Watanabe
1Department of Anesthesiology and Critical Care, Higashi Omiya General Hospital, Saitama 337-0051.
This case study highlights prolonged hypercapnia in an elderly patient with reduced lung function after surgery. Phrenic nerve palsy and sedation likely contributed to this respiratory complication.
Area of Science:
- Anesthesiology
- Pulmonology
- Geriatric Medicine
Background:
- An 83-year-old female with a history of lung cancer, rheumatoid arthritis, and pneumonia underwent surgery for bilateral extremity fractures.
- The patient presented with thoracic fluid retention, indicating compromised respiratory reserve.
Observation:
- Spinal anesthesia for femoral fracture repair was followed by interscalene brachial plexus block and sedation for olecranon fracture surgery.
- Post-block, the patient experienced a significant drop in oxygen saturation and required intubation due to severe hypercapnia (PaCO2 > 150 mmHg).
Findings:
- Following extubation, the patient required mask CPAP and exhibited persistent hypercapnia (PaCO2 90-100 mmHg) for three days.
- Phrenic nerve palsy, potentially induced by the interscalene block, combined with sedation and pre-existing lung disease, is suspected as the cause of prolonged hypercapnia.
Implications:
- This case underscores the importance of careful anesthetic management and monitoring in elderly patients with diminished lung function.
- It highlights the potential for prolonged hypercapnia resulting from the combined effects of regional anesthesia, sedation, and pre-existing respiratory compromise.
Related Concept Videos
Acute Respiratory Failure-III
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Hyperpnea and Hyperventilation
Pneumothorax II: Pathophysiology
Cardiopulmonary Resuscitation II: ACLS Airway Management
Alterations in Respiration II
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...
